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Filtered Search Results
Medchemexpress LLC 4-PPBP maleate | 201216-39-9 | MFCD00209909 | 99.6% | 409.52 g·mol-1 | C25H31NO4 | 25 MG
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4-PPBP maleate is a research-grade small-molecule sigma-1 receptor ligand and NMDA receptor modulator supplied as the maleate salt. It is intended for in vitro and preclinical studies and is not for human or clinical use. The compound is well characterized and provided with analytical purity suitable for laboratory research.
- Potent sigma-1 receptor ligand and agonist.
- Selective, non-competitive modulator of NR1a/2B NMDA receptors.
- Supplied as the maleate salt for stability and handling.
- High purity suitable for research applications (approximately 99.6%).
- Well-characterized molecular identity: C25H31NO4; MW 409.52 g·mol-1.
- Available in small laboratory pack sizes (25 mg).
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Medchemexpress LLC Dizocilpine maleate | 77086-22-7 | C20H19NO4 | 100 MG
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Dizocilpine maleate is a potent, selective, and non-competitive NMDA receptor antagonist. It effectively blocks currents induced by N-Me-D-Asp and can be utilized in various research applications, including inducing schizophrenia models.
- Potent, selective, and non-competitive NMDA receptor antagonist
- Causes progressive, long-lasting blockade of current induced by N-Me-D-Asp
- Used to induce schizophrenia models
- Kd of 37.2 nM in rat brain membranes
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Pfaltz & Bauer DI(2-ETHYLHEXYL) FUMARAT 50G
Di(2-ethylhexyl) fumarate 50G CAS# 141-02-6
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Apexbio Technology LLC WAY-100635 maleate salt 1092679-51-0 100mg
WAY-100635 maleate salt (CAS 1092679-51-0) is a selective antagonist of the serotonin 5-HT1A receptor subtype It demonstrates high potency with a reported pIC50 value of 8 87 and displays over 100-fold selectivity relative to other serotonin receptor isoforms and common neurotransmitter receptor classes Due to its specific interaction with 5-HT1A receptors WAY-100635 maleate is frequently applied in neuroscience research to elucidate serotonin-mediated pathways and associated physiological or behavioral responses
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Medchemexpress LLC Sumanirole maleate | 179386-44-8 | 99.8% | C15H17N3O5 | 50 MG
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Sumanirole maleate is a highly selective full agonist of the D2 receptor, exhibiting an ED50 of approximately 46 nM. This compound is significant in the study of Parkinson's disease and restless leg syndrome. It serves as a valuable research tool for investigating neurobiological mechanisms that are specifically linked to dopamine D2 receptor activity.
- Highly selective full agonist of the D2 receptor.
- Involved in research concerning Parkinson's disease.
- Used in the study of restless leg syndrome.
- Aids in identifying neurobiological mechanisms dependent on D2 receptor linkage.
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eMolecules 34675-24-6 | (-)-DIMENTHYL FUMARATE | AstaTech | MFCD00075423 | 392.580 | C24H40O4 | 95.000 | CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)\C=C\C(=O)O[C@H]1C[C@@H](C)CC[C@@H]1C(C)C | 1g | 410712751
(-)-DIMENTHYL FUMARATE | AstaTech | 34675-24-6 | MFCD00075423 | 392.580 | C24H40O4 | 95.000 | CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)\C=C\C(=O)O[C@H]1C[C@@H](C)CC[C@@H]1C(C)C | 1g | 410712751
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Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.84% | 391.42 | 1 ML
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Omigapil maleate (CGP3466B) is an orally active GAPDH nitrosylation inhibitor. It has been shown to abrogate Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. This compound holds potential for research in Alzheimer's disease and congenital muscular dystrophy (CMD), and it also acts as an apoptosis inhibitor. Additionally, Omigapil maleate is a click chemistry reagent, possessing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Orally active GAPDH nitrosylation inhibitor
- Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction abrogator
- Potential for Alzheimer's disease research
- Apoptosis inhibitor
- Can be used for congenital muscular dystrophy (CMD) research
- Click chemistry reagent with an Alkyne group for CuAAc reactions
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Medchemexpress LLC Cediranib maleate | 857036-77-2 | 99.95% | 25 MG
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Cediranib maleate is a highly potent, orally available VEGFR inhibitor. It demonstrates inhibitory activity against Flt1, KDR, Flt4, PDGFRα, PDGFRβ, and c-Kit. This compound is intended for research use only.
- Inhibits VEGF-stimulated proliferation and KDR phosphorylation in human umbilical vein endothelial cells.
- Reduces vessel area, length, and branching in a fibroblast/endothelial cell coculture model.
- Ablates experimental (VEGF-induced) angiogenesis in vivo.
- Inhibits endochondral ossification and corpora luteal development.
- Dose-dependently inhibits the growth of human tumor xenografts (colon, lung, prostate, breast, and ovary) in athymic mice.
- Shows a reduction in microvessel density within tumors, indicating vascular regression.
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Medchemexpress LLC Flupirtine Maleate | 75507-68-5 | 100.0% | 420.39 | 100 MG
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Flupirtine Maleate is an orally active, blood-brain barrier-crossing non-opioid analgesic and neuroprotective agent. It functions as a neuronal potassium channel opener (Kv7 activator), an NMDA receptor antagonist, and a GABA receptor activator. This agent is suitable for research related to focal cerebral ischemia, pain, Alzheimer's disease, or multiple sclerosis.
- Stabilizes blood-brain barrier integrity.
- Reduces oxidative stress and brain leukocyte infiltration.
- Enhances angioneurogenesis.
- Suppresses calcium influx.
- Stabilizes neuronal resting membrane potential.
- Counteracts focal cerebral ischemia.
- Exhibits analgesic and muscle relaxant properties.
- Protects neurons from excitotoxic, ischemic, or cytokine-mediated death.
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Medchemexpress LLC Perhexiline maleate | 6724-53-4 | MFCD00057329 | 98.0% | 393.56 | C23H39NO4 | 10 MG
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Perhexiline maleate is the maleate salt of perhexiline, a small-molecule inhibitor of carnitine palmitoyltransferase 1 and 2 (CPT1/CPT2) used in preclinical research to probe mitochondrial fatty-acid metabolism, cancer biology, and cardiovascular disease models. It is provided as a solid salt intended for biochemical and cell-based assays.
- Inhibits CPT1 and CPT2, reducing fatty-acid oxidation
- Maleate salt form improves aqueous handling for assays
- Available in research-scale quantities, including 10 mg
- High reported purity suitable for in vitro and preclinical studies
- Documented chemical identifiers include CAS 6724-53-4 and molecular weight 393.56
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Medchemexpress LLC Indacaterol maleate | 753498-25-8 | 99.8% | C28H32N2O7 | 1 ML
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Indacaterol maleate is an orally active, ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. It functions by inhibiting NF-κB activity in a β-arrestin2-dependent manner. This chemical property contributes to preventing further lung damage and improving lung function in conditions like chronic obstructive pulmonary disorder (COPD). It also has potential applications in cardiovascular disease research.
- Acts as an ultra-long-acting β2 adrenergic receptor (ADRB2) agonist.
- Inhibits NF-κB activity via a β-arrestin2-dependent mechanism.
- Suppresses MMP-9 mRNA expression and activity.
- Reduces cell migration and inhibits NF-κB nuclear translocation.
- Active in normalizing cardiac remodeling in heart failure models.
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Selleck Chemical LLC Perhexiline maleate
Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 M and 148 M for rat heart CPT1 and liver CPT1 respectively and also inhibits carnitine palmitoyltransferase 2 (CPT2)
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Sigma Aldrich Fine Chemicals Biosciences GR 89696 fumarate salt solid | 126766-32-3 | MFCD00274044 | 25MG
GR 89696 fumarate salt solid | Mol Wt: 530.4 | 126766-32-3 | MFCD00274044 | 25MG
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Selleck Chemical LLC Cediranib Maleate S5242-10mg
Cediranib Maleate (AZD2171) is the maleate salt of Cediranib which is a potent inhibitor of VEGFR with IC50 of 1 nM and also inhibits Flt1/4 with IC50 of 5 nM/ 3 nM
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Chem-Impex International, Inc. Dimethyl acetylenedicarboxylate | 762-42-5 | MFCD00008456 | 25G
Dimethyl acetylenedicarboxylate, 762-42-5, MFCD00008456, 25G
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